Jun 13, 2023
Would you want to know
when
you are going to die?
In this episode of the Biohacking Superhuman Performance podcast, I
chat with Hannah Went, Director of Operations at TruDiagnostic,
about the stories certain biomarkers can tell about our present
health and our future health. From predictors of lifespan to
predictors of diseases, there is a large array of biomarkers we can
target to help identify a patient’s biological
age.
Hannah also shares what lifestyle changes someone can implement to
increase their longevity and reverse the clock on their biological
age so that it either equals or underpasses a person’s
chronological age. From limiting alcohol consumption to caloric
restriction, there is a multitude of lifestyle changes one can make
to increase their lifespan.
Hannah Went has a lifelong passion for longevity and breakthrough,
disruptive technologies that drive radical improvement to the human
condition. She attended the University of Kentucky and graduated
with a degree in Biology. After graduation, she worked for the
International Peptide Society as their Director of Research and
Content. Through work in the integrative medicine industry, Hannah
saw an opportunity for methylation-based age diagnostics and
started TruDiagnostics in 2020. TruDiagnostic is a company focusing
on methylation array-based diagnostics for life extension and
preventive healthcare serving functional medicine
providers.
Thank you to our sponsors for making this episode
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Find more from Nathalie:
Find more from Hannah:
What we discuss:
02:29: What do all of these biomarker tests do?
06:14: What is an R-value?
09:24: What are first-generation clocks looking at?
13:22: What values do the second generation of clocks look
at?
14:11: Is the GrimAge indicator an accurate predictor of
lifespan?
17:03: What are the different metabolomic and proteomic approaches
to biomarkers?
21:43: Why are third-generation clocks better than the precedent
ones?
22:43: What can accelerate a person’s biological age?
27:57: Can exercise age you?
28:54: What does telomeres length mean about your
health?
34:18: Against what population are your biomarkers usually
compared?
36:40: What have the latest clinical studies found?
40:25: In which cases would your clock stay consistent over the
years?
43:44: Can we determine which areas in our bodies are aging
faster?
47:00: Can caloric restriction reverse biological
aging?
52:01: What is the quicksilver protocol?
54:47: How often should you do a TruDiagnostic test?
56:03: What are the top lifestyle hacks to slow chronological
aging?
57:30: Which supplements should you take?
58:50: Where to learn more about Hannah
Key takeaways:
-
Three different types of clocks examine biomarkers in terms of
longevity: first-generation clocks, second-generation clocks, and
third-generation clocks. They all examine different values that are
indicative of longevity. Right now, the most precise clock is the
third-generation clock as it is trained on direct biomarkers of
health and disease, such as grip strength in people, aging-related
brain shrinkage, dental health, lung function, and
more.
-
Most of us have a biological age that is more advanced than our
chronological age. While some factors influencing this premature
aging can’t be changed, our biological age is heavily influenced by
our lifestyle. Alcohol consumption, tobacco usage, sleeping
patterns, stress management, and exercise are some of the few
lifestyle aspects that can reduce our lifespan.